Development of Clinical Study Documents

Consulting services associated with the design of clinical studies and the preparation of associated documents
Authorship of ICH-compliant study protocols
Preparation of informed consent/assent documents
Assistance with institutional review board/investigational ethics committee (IRB/IEC) submissions
Design and printing of case report forms and other data collection instruments (eg, subject diaries)
Authorship of investigator brochures
Preparation of Regulatory Submission Materials

Authorship of information intended for inclusion in regulatory agency briefing packets
Complete authorship of ICH-compliant clinical study reports (CSRs)
Development of clinical sections (ie, Module 2) within the common technical document (CTD) framework
Development of clinical portions of premarketing approval applications (PMAs) and other device submission dossiers (eg, 510[k] applications)
Authorship of stand-alone integrated summaries of efficacy and safety
Publication of reports and dossiers in an FDA-compliant, portable document format (PDF)
Preparation of granulated CSRs for "drag and drop" inclusion in electronic CTD submissions
Authorship of Scientific Communication Materials

Authorship of manuscripts compliant with the Consolidated Standards of Reporting Trials (CONSORT) statement
Management and tracking of online journal submissions
Generation of supporting figures in encapsulated postscript (EPS) format to meet journal requirements
Authorship and submission of poster abstracts
Design and printing of poster presentations
Authorship of product monographs, including the layout and presentation of text, figures, and tables
Consulting and Quality Control Activities

Consulting regarding clinical conduct best practices, submission requirements, and development of complex messaging
Assistance with literature searches conducted across medical, toxicological, and chemical databases
Summarization and presentation of detailed literature search results
Preparation of document templates and style guides in accordance with best practices and both FDA- and ICH-requirements
Proofreading of written materials to confirm accuracy and appropriateness of content
Quality control reviews of written materials to ensure consistency, accuracy, and guideline compliance
Medical editing services